All Comments by Benjamin Wolozin

  1. ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
  2. Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity.
  3. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
  4. Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts.
  5. Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.
  6. Statins and the risk of dementia.
  7. Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
  8. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.
  9. Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.
  10. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.
  11. A novel peptide prevents death in enriched neuronal cultures.
  12. Alzheimer's disease: model behaviour.
  13. Cholesterol Again Linked with Alzheimer's
  14. Suspects for Aβ Generation Spotted Together, En Route to Nerve Terminal
  15. Aβ Abets α-Synuclein