All Comments by Benjamin Wolozin

  1. Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease.
  2. Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.
  3. Essential role for cholesterol in synaptic plasticity and neuronal degeneration.
  4. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation.
  5. Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
  6. Synucleins are a novel class of substrates for G protein-coupled receptor kinases.
  7. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.
  8. Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.
  9. Parkinson disease neuropathology: later-developing dementia and loss of the levodopa response.
  10. Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase.
  11. Cholesterol Again Linked with Alzheimer's
  12. Suspects for Aβ Generation Spotted Together, En Route to Nerve Terminal
  13. Aβ Abets α-Synuclein