All Comments by Benjamin Wolozin

  1. SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
  2. Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy.
  3. Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity.
  4. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
  5. Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts.
  6. ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
  7. Statins and the risk of dementia.
  8. Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
  9. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.
  10. Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.
  11. Cholesterol Again Linked with Alzheimer's
  12. Suspects for Aβ Generation Spotted Together, En Route to Nerve Terminal
  13. Aβ Abets α-Synuclein