All Comments by Benjamin Wolozin

  1. In New Role for TDP-43, Scientists Say it Controls Protein Synthesis
  2. ALS Research ‘Gels’ as Studies Tie Disparate Genetic Factors Together
  3. Field Loses Another Pioneer with Passing of Allen Roses, 73
  4. ALS Protein Said to Liquefy, Then Freeze en Route to Disease
  5. Angiotensin-converting enzyme inhibitors and amyotrophic lateral sclerosis risk: a total population-based case-control study.
  6. Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.
  7. Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits.
  8. Larry Sparks, of Alzheimer’s-Cholesterol Fame, Dies at 63
  9. β-amyloid inhibits protein prenylation and induces cholesterol sequestration by impairing SREBP-2 cleavage.
  10. A "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport.
  11. Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease.
  12. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.
  13. Law and Disorder—APPswe Patent Suits Raise Ruckus Again
  14. Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.
  15. Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.