All Comments by Michael Lardelli

  1. Presenilin-1 Targeted Morpholino Induces Cognitive Deficits, Increased Brain Aβ1-42 and Decreased Synaptic Marker PSD-95 in Zebrafish Larvae.
  2. Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase.
  3. Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
  4. Lodged in Late Endosomes, Presenilin 2 Churns Out Intraneuronal Aβ
  5. Pathogenic Presenilin Mutations Generate Aβ43
  6. ApoE4 upregulates the activity of mitochondria-associated ER membranes.
  7. Mutant Presenilin Knock-in Mice Mimic Knockouts, Stir Old Debate
  8. Novel presenilin mutations within Moroccan patients with Early-Onset Alzheimer's Disease.
  9. Mitochondria-associated ER membranes in Alzheimer disease.
  10. The capillary dysfunction hypothesis of Alzheimer's disease.
  11. Upregulated function of mitochondria-associated ER membranes in Alzheimer disease.
  12. Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins.
  13. Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans.
  14. More Than APP—γ-Secretase, Metalloproteases Control Neurotransmission
  15. Reimagining Alzheimer's Disease—Time for Bright New Ideas?