All Comments by Charles Glabe

  1. Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.
  2. Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS.
  3. Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
  4. Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation.
  5. IV immunoglobulin is associated with a reduced risk of Alzheimer disease and related disorders.
  6. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.
  7. Molecular basis for passive immunotherapy of Alzheimer's disease.
  8. Enhancing Aβ Fibrillization Boosts Mouse Memory
  9. Salzburg: Aβ’s N-terminal Shenanigans
  10. Lethal recessive myelin toxicity of prion protein lacking its central domain.
  11. Side chain-dependent stacking modulates tau filament structure.
  12. Consensus features in amyloid fibrils: sheet-sheet recognition via a (polar or nonpolar) zipper structure.
  13. Nanotools for megaproblems: probing protein misfolding diseases using nanomedicine modus operandi.
  14. Prefibrillar amyloid aggregates could be generic toxins in higher organisms.
  15. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.